2-(4-氯苯基)-苯并噁唑合成路线 （共 59 条）
反应条件
1: 99 percent / tetrahydrofuran / 24 h / 20 °C
2: 99 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
1: 99 percent / tetrahydrofuran / 24 h / 20 °C
2: 99 percent / CuI; Cs2CO3; 1,10-phenanthroline / 1,2-dimethoxy-ethane / 24 h / Heating
View Scheme
参考文献
Evindar, Ghotas; Batey, Robert A.
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808
反应条件
1: hydrazine hydrate; water / tetrahydrofuran / 0.5 h / 0 °C / |Inert atmosphere
2: dichloro bis(acetonitrile) palladium(II); sodium carbonate; copper diacetate; tetrabutylammomium bromide; 1,10-phenanthroline / dimethyl sulfoxide; 1,4-dioxane / 4.58 h / 20 - 100 °C / |Inert atmosphere
View Scheme
参考文献
Yu, Xinzhang; Li, Xingwei; Wan, Boshun
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 37 p. 7479 - 7482
反应条件
in benzene
T=60°C; 24 h; Further byproducts given;
参考文献
Leardini, Rino; McNab, Hamish; Nanni, Daniele
Tetrahedron, 1995 , vol. 51, # 44 p. 12143 - 12158
反应条件
1: 73 percent / p-toluenesulfonic acid / toluene / Heating
2: 1.) sodium ethoxide / 1.) ethanol, reflux, 2.) benzene, reflux, 2 h
3: 23 percent / di-iso-propyl peroxydicarbonate / benzene / 24 h / 60 °C
View Scheme
参考文献
Leardini, Rino; McNab, Hamish; Nanni, Daniele
Tetrahedron, 1995 , vol. 51, # 44 p. 12143 - 12158
反应条件
1: hydrazine / methanol; chloroform; water / 12 h / 20 °C
2: acetic acid / water / 0.5 h / 20 °C
3: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 3.5 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
1: acetic acid / water / 0.5 h / 20 °C
2: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 3.5 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
1: pyridine; copper(I) bromide / dichloromethane / 48 h / 20 °C / Molecular sieve
2: hydrazine / methanol; chloroform; water / 12 h / 20 °C
3: acetic acid / water / 0.5 h / 20 °C
4: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 3.5 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
参考文献
Bywater et al.
Journal of the American Chemical Society, 1945 , vol. 67, p. 905
反应条件
di-tert-butyl peroxide; FeBr2
T=110°C; Inert atmosphere;
参考文献
Gu, Lijun; Jin, Cheng; Guo, Junming; Zhang, Lizhu; Wang, Wei
Chemical Communications, 2013 , vol. 49, # 93 p. 10968 - 10970
