2-(甲基硫代)-4-嘧啶甲腈合成路线 (共 4 条)
反应条件
pyridine 4 h; Heating / reflux;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2006/9889 A1, 2006 ;
Location in patent: Page/Page column 56 ;
WO 2006/009889 A1
反应条件
in tetrahydrofuran 2 h; Heating / reflux;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1424336 A1, 2004 ;
Location in patent: Page 210 ;
反应条件
in dichloromethane 0.5 h; Ambient temperature;
参考文献
Hermann, Klaus; Simchen, Gerhard
Liebigs Annalen der Chemie, 1981 , # 2 p. 333 - 341
反应条件
1: 94 percent / benzene / 1) 0 deg C; 2) room temperature, 1h 2: 87 percent / CH2Cl2 / 0.5 h / Ambient temperature View Scheme
参考文献
Liebigs Annalen der Chemie, , # 2 p. 333 - 341