2-氯-4-乙氧基-6-甲基-烟酸乙酯合成路线 （共 6 条）
反应条件
hydrogen; potassium acetate; palladium on activated charcoal in isopropyl alcohol T=20°C; P=3000.2 Torr; 48 h;
参考文献
Mittelbach, Martin
Synthesis, 1988 , # 6 p. 479 - 480
反应条件
1: 74 percent / KOAc, H2 / 10percent Pd/C / propan-2-ol / 48 h / 20 °C / 3000.2 Torr 2: 83 percent / conc. aq. HCl / 24 h / Heating View Scheme
参考文献
Mittelbach, Martin
Synthesis, 1988 , # 6 p. 479 - 480
反应条件
AMINOHIPPURATE SODIUM in ethanol
参考文献
ACTELION PHARMACEUTICALS LTD.; Hilpert, Kurt; Hubler, Francis; Kimmerlin, Thierry; Renneberg, Dorte; Stamm, Simon; Murphy, Mark
Patent: US2014/163035 A1, 2014 ;
Location in patent: Page/Page column ;
参考文献
ACTELION PHARMACEUTICALS LTD; HILPERT, Kurt; HUBLER, Francis; KIMMERLIN, Thierry; MURPHY, Mark; RENNEBERG, Dorte; STAMM, Simon
Patent: WO2013/14587 A1, 2013 ;
Location in patent: Page/Page column 79 ;
WO 2013/014587 A1
参考文献
Mittelbach, Martin
Synthesis, 1988 , # 6 p. 479 - 480
反应条件
1: 89 percent / POCl3 / 4 h / 140 °C
2: 76 percent / Na / 3 h / 60 °C
View Scheme
参考文献
Mittelbach, Martin
Synthesis, 1988 , # 6 p. 479 - 480
