N,N-二甲基-1,3-二氨基丙烷合成路线 （共 206 条）
反应条件
T=150 - 175°C; 4.16 - 5.16 h;
参考文献
Evonik Goldschmidt GmbH
Patent: US2009/54521 A1, 2009 ;
Location in patent: Page/Page column 5 ;
反应条件
phenol
T=95 - 100°C; 1.5 h;
参考文献
Kitchen, S. E.; Wang, Yueh-Hwa; Baumstark, A. L.; Wilson, W. D.; Boykin, D. W.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 940 - 944
反应条件
1: 91 percent / 120 - 130 °C
2: 90 percent / propan-2-ol / 8 h / Heating
View Scheme
参考文献
Limanov, V. E.; Epshtein, A. E.; Yakushkin, M. I.; Telegin, M. Yu.; Kotov, V. I.; et al.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 2 p. 85 - 87
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 2 p. 28 - 30
反应条件
hydrogen; 1 Pd/C
T=120°C; P=77574.3 Torr;
参考文献
Huntsman Petrochemical Corporation
Patent: US2004/15016 A1, 2004 ;
Location in patent: Page 2 ;
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in N,N-dimethyl-formamide
T=0 - 20°C; 20 h;
参考文献
Chae, Pil Seok; Sadaf, Aiman; Gellman, Samuel H.
Chemistry - An Asian Journal, 2014 , vol. 9, # 1 p. 110 - 116
反应条件
in ethanol
T=10°C; 22 h; Heating / reflux;
参考文献
RUDER BOSKOVIC INSTITUTE
Patent: WO2005/100306 A1, 2005 ;
Location in patent: Page/Page column 3; figure 1 ;
