反应条件
1: propargyl alcohol With zirconocene dichloride; diisobutylaluminium hydride in tetrahydrofuran; hexane T=0 - 23°C; 0.5 h; Inert atmosphere; 2: (Z)-1-iodo-1-octene With PEPPSI-IPr catalyst in tetrahydrofuran; hexane T=23°C; Negishi coupling reaction; 12 h; Inert atmosphere; optical yield given as percent destereoselective reaction;
参考文献
Wang, Guangwei; Mohan, Swathi; Negishi, Ei-Ichi
Proceedings of the National Academy of Sciences of the United States of America, 2011 , vol. 108, # 28 p. 11344 - 11349
