4-甲基-4-戊烯-2-炔-1-醇合成路线 （共 9 条）
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran
T=-78 - 20°C; 2 h;
参考文献
Braverman, Samuel; Pechenick-Azizi, Tatiana; Gottlieb, Hugo E.; Sprecher, Milon
Synthesis, 2011 , # 11 p. 1741 - 1750
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine in tetrahydrofuran
T=20 - 60°C; Inert atmosphere;
参考文献
Park, Jisu; Kim, Sung Hong; Lee, Phil Ho
Organic Letters, 2008 , vol. 10, # 21 p. 5067 - 5070
参考文献
Newman; Fones; Booth
Journal of the American Chemical Society, 1945 , vol. 67, p. 1054
Full Text Show Details
I.G.Farbenind.
Patent: DE526390 , 1925 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 18, p. 2886
反应条件
n-butyllithium; alkaline hydrogen peroxide
1.) THF, -78 deg C, 0.5 h; room temperature, 1.5 h; Yield given. Multistep reaction;
参考文献
Soundararajan, Raman; Li, Guisheng; Brown, Herbert C.
Tetrahedron Letters, 1994 , vol. 35, # 48 p. 8961 - 8964
反应条件
toluene-4-sulfonic acid; 1,2,3-benzenetriol
参考文献
Vlasov,V.M. et al.
Journal of Organic Chemistry USSR (English Translation), 1966 , vol. 2, p. 597 - 598
Zhurnal Organicheskoi Khimii, 1966 , vol. 2, # 4 p. 595 - 597
参考文献
Vlasov,V.M. et al.
Journal of Organic Chemistry USSR (English Translation), 1967 , vol. 3, p. 261 - 263
Zhurnal Organicheskoi Khimii, 1967 , vol. 3, # 2 p. 277 - 280
反应条件
ethylmagnesium bromide
1.) ether, room temperature, 1.5 h, 2.) overnight; Yield given. Multistep reaction;
参考文献
Laird, Trevor; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2033 - 2048
参考文献
Duboudin,J.G.; Jousseaume,B.
Journal of Organometallic Chemistry, 1979 , vol. 168, p. 1 - 11
参考文献
Hoffmann, H. M. R.; Krumwiede, D.; Mucha, B.; Oehlerking, H. H.; Prahst, G. W.
Tetrahedron, 1993 , vol. 49, # 40 p. 8999 - 9018
