(2S)-3-[[(叔丁基)二甲基硅烷基]氧基]-2-甲基-1-丙醇合成路线 （共 14 条）
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane T=-78°C; 0.5 h; 2: With sodium hydroxide; water in hexane; dichloromethane; tert-butyl methyl ether T=20°C;
参考文献
Kong, Ke; Moussa, Ziad; Lee, Changsuk; Romo, Daniel
Journal of the American Chemical Society, 2011 , vol. 133, # 49 p. 19844 - 19856
反应条件
1: 90 percent / imidazole / dimethylformamide / 0 °C 2: 78 percent / BH3*Me2S; Et3N / methanol; tetrahydrofuran / 25 °C View Scheme
参考文献
Santaniello, Enzo; Casati, Silvana; Ciuffreda, Pierangela; Gamberoni, Luca
Tetrahedron Asymmetry, 2004 , vol. 15, # 20 p. 3177 - 3179
反应条件
diisobutylaluminum hydride in tetrahydrofuran; hexane T=-20°C; 1 h;
参考文献
Ihara, Masataka; Takahashi, Masanobu; Taniguchi, Nobuaki; Yasui, Ken; Fukumoto, Keiichiro; Kametani, Tetsuji
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 897 - 903
反应条件
in chloroform T=30°C; 15 h; Pseudomonas fluorescens lipase (PFL);
参考文献
Grisenti; Ferraboschi; Manzocchi; Santaniello
Tetrahedron, 1992 , vol. 48, # 18 p. 3827 - 3834
反应条件
palladium 10 on activated carbon; hydrogen in tert-butyl methyl ether P=760.051 Torr; Inert atmosphere;
参考文献
Reiss, Tomislav; Breit, Bernhard
Chemistry - A European Journal, 2009 , vol. 15, # 26 p. 6345 - 6348
反应条件
vinyl acetate in chloroform T=30°C; 24 h; Pseudomonas fluorescens lipase (PFL);
参考文献
Grisenti; Ferraboschi; Manzocchi; Santaniello
Tetrahedron, 1992 , vol. 48, # 18 p. 3827 - 3834
反应条件
nitrogen; diisobutylaluminium hydride in tetrahydrofuran; water; N,N-dimethyl-formamide; toluene
参考文献
Merck and Co., Inc.
Patent: US4940797 A1, 1990 ;
反应条件
nitrogen; diisobutylaluminium hydride in tetrahydrofuran; water; N,N-dimethyl-formamide; toluene
参考文献
Merck and Co., Inc.
Patent: US5155228 A1, 1992 ;
反应条件
methanol; diisobutylaluminium hydride in toluene T=-42°C; Inert atmosphere;
参考文献
Webb, Damien; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 2 p. 568 - 571
反应条件
potassium hydroxide in methanol 5 h; Heating;
参考文献
Scheck, Michael; Waldmann, Herbert
Canadian Journal of Chemistry, 2002 , vol. 80, # 6 p. 571 - 576
