1: 4-fluoro-1-iodobenzene With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 2: meta-bromobenzonitrile With PEPPSITM-IPr in tetrahydrofuran T=25°C; Kumada coupling reaction; 0.0833333 h; Inert atmosphere;

tetra-butylammonium acetate; Pd EnCat-30TM in acetonitrile T=140°C; Suzuki cross-coupling; 0.25 h; microwave irradiation;

potassium acetate; 18-crown-6 ether 1.5 h; Ambient temperature; Yield given. Yields of byproduct given;