2-(2-溴乙酰基)噻吩合成路线 （共 37 条）
反应条件
bromine; aluminium trichloride in diethyl ether 0.25 h;
参考文献
Adamczewska; Barker; Huddleston; Wood
Synthetic Communications, 1996 , vol. 26, # 6 p. 1083 - 1096
反应条件
in chloroform; ethyl acetate
参考文献
Wagle; Dilip R.; Fang; Sheng-Ding; Rho; Taikyun; Egan; John J.; Vasan; Sara; Ulrich; Peter; Cerami; Anthony
Patent: US6121300 A1, 2000 ;
反应条件
[BMIM(SO3H)][OTf]; N-bromosuccinmide T=55°C; 0.166667 h; Green chemistry;
参考文献
Molecules, , vol. 18, # 1 p. 74 - 96
反应条件
bromine in dichloromethane T=-40°C;
参考文献
Dubac; Gaset; Maraval
Synthetic Communications, 1991 , vol. 21, # 1 p. 11 - 16
反应条件
n-butyllithium; lithium diisopropyl amide Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 50, # 25 p. 5140 - 5142
参考文献
Justus Liebigs Annalen der Chemie, , vol. 430, p. 104
参考文献
Chemische Berichte, , vol. 19, p. 2893
反应条件
sodium carbonate in neat (no solvent, solid phase) T=20°C; Hantzsch Thiazole Synthesis; 0.0833333 h; Green chemistry;
参考文献
Aggarwal, Ranjana; Kumar, Sunil; Singh, Shiv P.
Journal of Sulfur Chemistry, 2012 , vol. 33, # 5 p. 521 - 525,5
反应条件
in ethanol 6 h; Heatingalso reaction with other phenacyl bromides; Product distribution;
参考文献
Singh, S. P.; Sehgal, Subhash; Singh, Lukhvinder; Dhawan, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 154 - 155
反应条件
1: NaH / tetrahydrofuran / 0.5 h / Ambient temperature 2: acetic anhydride / 0.25 h / 40 °C View Scheme
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502
