2,3-二甲基-3-丁烯-2-醇合成路线 （共 74 条）
反应条件
ozone in hexane
T=0°C; Further byproducts given;
参考文献
Murray, Robert W.; Kong, Wei; Rajadhyaksha, Shirish N.
Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 315 - 321
反应条件
1: With potassium tert-butylate in pentane
T=-60 - 0°C; Inert atmosphere;
2: With ammonium chloride in pentane
0.25 h;
3: With water
参考文献
Galy, Nicolas; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2010 , vol. 51, # 4 p. 695 - 697
反应条件
methyl α-hydroperoxy-α,α-diphenylacetate in chloroform
T=60°C; further temperature and solvents; anaerobic conditions; Rate constant;
参考文献
Bruice, Thomas C.; Noar, J. Barry; Ball, Sheldon S.; Venkataram, U. V.
Journal of the American Chemical Society, 1983 , vol. 105, # 8 p. 2452 - 2463
反应条件
1: With tert.-butylhydroperoxide; Al tri-t-BuO- in benzene
T=20°C; 24 h;
2: With sulfuric acid in diethyl ether
Title compound not separated from byproducts;
参考文献
Martynova; Stepovik; Dodonov
Russian Journal of General Chemistry, 2001 , vol. 71, # 5 p. 736 - 741
反应条件
1: 94 percent / pyridine / 3 h / 0 °C
2: 71 percent / NaN3 / dimethylsulfoxide; H2O / 16 h / 90 °C
3: 25 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
4: 9.1 percent Chromat. / NaNO2, 2N HClO4 / H2O / 1 h
View Scheme
参考文献
Guenther, Bernd-Rainer; Kirmse, Wolfgang
Liebigs Annalen der Chemie, 1980 , # 4 p. 518 - 532
反应条件
1: 25 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
2: 9.1 percent Chromat. / NaNO2, 2N HClO4 / H2O / 1 h
View Scheme
参考文献
Guenther, Bernd-Rainer; Kirmse, Wolfgang
Liebigs Annalen der Chemie, 1980 , # 4 p. 518 - 532
反应条件
1: 71 percent / NaN3 / dimethylsulfoxide; H2O / 16 h / 90 °C
2: 25 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
3: 9.1 percent Chromat. / NaNO2, 2N HClO4 / H2O / 1 h
View Scheme
参考文献
Guenther, Bernd-Rainer; Kirmse, Wolfgang
Liebigs Annalen der Chemie, 1980 , # 4 p. 518 - 532
反应条件
1: With potassium tert-butylate in pentane
T=-60 - 0°C;
2: With ammonium chloride in pentane
0.25 h;
3: With water
参考文献
Galy, Nicolas; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2010 , vol. 51, # 4 p. 695 - 697
反应条件
sodium in ammonia
Yield given;
参考文献
Rodriguez, J.; Dulcere, J-P; Bertrand, M.
Tetrahedron Letters, 1984 , vol. 25, # 5 p. 527 - 528
反应条件
1: With tert.-butylhydroperoxide; Al tri-t-BuO- in benzene
T=20°C; 24 h;
2: With sulfuric acid in diethyl ether
Title compound not separated from byproducts;
参考文献
Martynova; Stepovik; Dodonov
Russian Journal of General Chemistry, 2001 , vol. 71, # 5 p. 736 - 741
