2-苄基-2,4-环己二酮合成路线 （共 13 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 12 h; Inert atmosphere;
参考文献
Shen, Si-Da; Zhang, Gui-Ping; Lei, Min; Hu, Li-Hong
Arkivoc, 2012 , vol. 2012, # 6 p. 204 - 213
反应条件
potassium hydroxide; Aliquatreg; 336 in N,N-dimethyl-formamide T=120°C; 4 h;
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
in N,N-dimethyl-formamide
参考文献
Ortho Pharmaceutical Corporation
Patent: US4761413 A1, 1988 ;
US 4761413 A
反应条件
sodium methylate in N,N-dimethyl-formamide 0.5 h; Ambient temperature;
参考文献
Oriyama, Takeshi; Noda, Kojiro; Yatabe, Kaori
Synlett, 1997 , vol. 1997, # 6 p. 701 - 703
反应条件
cesium fluoride in N,N-dimethyl-formamide 12 h; Ambient temperature;
参考文献
Oriyama, Takeshi; Noda, Kojiro; Yatabe, Kaori
Synlett, 1997 , vol. 1997, # 6 p. 701 - 703
反应条件
ethanol; sodium ethanolate
参考文献
Druey
Bulletin de la Societe Chimique de France, 1935 , vol. <5> 2, p. 1737,1740
参考文献
Schiff,H.; Pellizzari
Justus Liebigs Annalen der Chemie, 1883 , vol. 221, p. 378
反应条件
bromine in dichloromethane T=0 - 20°C; 3 h;
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
1: acetic acid; aqueous HNO3 2: sodium dithionite; aqueous ethanol View Scheme
参考文献
Baker; Kirby; Montgomery
Journal of the Chemical Society, 1932 , p. 2876,2878
反应条件
1: acetic acid; aqueous HNO3 2: concentrated aqueous HCl; acetic acid View Scheme
参考文献
Baker; Kirby; Montgomery
Journal of the Chemical Society, 1932 , p. 2876,2878
