4-氨基-2,6-二氯嘧啶合成路线 （共 20 条）
反应条件
pyridine; trichlorophosphate T=160°C; 2 h; Autoclaveneat (no solvent);
参考文献
Molecules, , vol. 17, # 4 p. 4533 - 4544
参考文献
Chemische Berichte, , vol. 36, p. 2234
Chemische Berichte, , vol. 34, p. 3363
参考文献
Journal of Organic Chemistry, , vol. 20, p. 829,833,835
参考文献
Chemische Berichte, , vol. 36, p. 2227
Chemische Berichte, , vol. 34, p. 3363
参考文献
Langerman; Banks
Journal of the American Chemical Society, 1951 , vol. 73, p. 3011
反应条件
phosphonium iodide; hydrogen iodide T=60 - 70°C;
参考文献
Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234
参考文献
Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234
反应条件
in methanol 2 h; Heating / reflux;
参考文献
MERCK SHARP and DOHME LIMITED
Patent: WO2005/47279 A1, 2005 ;
Location in patent: Page/Page column 34 ;
WO 2005/047279 A1
反应条件
N-ethyl-N,N-diisopropylamine in isopropyl alcohol T=75°C;
参考文献
Li, Chaomin; Rosenau, Andrew
Tetrahedron Letters, 2009 , vol. 50, # 43 p. 5888 - 5893
反应条件
in Sec-butyl alcohol T=20 - 102°C; 21 h; Reagent/catalystTemperatureTimeSolventConcentration;
参考文献
ASSIA CHEMICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.; MAJER, Maja, Sepelj; KRIZMANIC, Irena; VRBANEC, Gordana
Patent: WO2013/59572 A1, 2013 ;
Location in patent: Page/Page column 17; 18 ;
