2-环己基亚基环己烷-1-酮合成路线 （共 47 条）
反应条件
potassium hydroxide in water
T=74 - 165°C; P=600.06 - 9375.94 Torr; Purification / work up;
参考文献
Koninklijke DSM N.V.
Patent: EP1433774 A1, 2004 ;
Location in patent: Page 4-5 ;
反应条件
2-(trimethylsilyl)prop-2-enylzinc chloride; bis(acetylacetonate)nickel(II) in diethyl ether
1.) -15 deg C, 0.5 h, 2.) r.t., 18 h;
参考文献
Eshelby, James J.; Parsons, Philip J.; Crowley, Patrick J.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 2 p. 191 - 199
反应条件
Potassium peroxomonosulfate; silica gel in carbon dioxide
T=40°C; Baeyer-Villiger oxidation; P=187515 Torr;
参考文献
Gonzalez-Nunez, Maria E.; Mello, Rossella; Olmos, Andrea; Asensio, Gregorio
Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6432 - 6436
反应条件
in toluene
T=25°C; 3 h;
参考文献
Piotrowski, Andrzej M.; Malpass, Dennis B.; Boleslawski, Marek P.; Eisch, John J.
Journal of Organic Chemistry, 1988 , vol. 53, # 12 p. 2829 - 2835
反应条件
potassium hydroxide in toluene
T=190°C; 6.5 h; Further byproducts given;
参考文献
Bell, Thomas W.; Vargas, J. Ramon; Crispino, Gerard A.
Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1978 - 1987
反应条件
5-palladium/activated carbon; hydrogen in ethanol
T=139.84°C; P=11251.1 Torr; 3.25 h;
参考文献
Serna, Pedro; Lopez-Haro; Calvino; Corma, Avelino
Journal of Catalysis, 2009 , vol. 263, # 2 p. 328 - 334
反应条件
hydrogen in 1,4-dioxane
T=20°C; P=30003 Torr; 10 h;
参考文献
Sun, Meng; Du, Xiaobao; Kong, Xiangjin; Lu, Liang; Li, Yang; Chen, Ligong
Catalysis Communications, 2012 , vol. 20, p. 58 - 62
反应条件
bis(trimethylsilyl)dilithiomethane in tetrahydrofuran
T=-80°C; Yields of byproduct given;
参考文献
Eikema Hommes, N. J. R. van; Bickelhaupt, F.; Klumpp, G. W.
Tetrahedron Letters, 1988 , vol. 29, # 41 p. 5237 - 5240
反应条件
platinum on alumina; hydrogen in ethanol
T=119.84°C; P=7500.75 Torr; 0.666667 h;
参考文献
Serna, Pedro; Lopez-Haro; Calvino; Corma, Avelino
Journal of Catalysis, 2009 , vol. 263, # 2 p. 328 - 334
反应条件
1: With triethylamine
1 h; Inert atmosphere;
2: With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 3 h; Inert atmosphere;
参考文献
Marek, Ales; Klepetarova, Blanka; Elbert, Tomas
Collection of Czechoslovak Chemical Communications, 2011 , vol. 76, # 5 p. 443 - 456
