6-氧代-3,7-二甲基-嘌呤-2-醇钠合成路线 （共 4 条）
反应条件
1: dimethylformamide / 4.5 h / 110 °C 2: 57 percent / NaBH4, MeOH / 2-methyl-propan-2-ol / 1.25 h / 90 °C View Scheme
参考文献
Fischer, Bilha; Yefidoff, Revital; Major, Dan T.; Rutman-Halili, Irit; Shneyvays, Valadimir; Zinman, Tova; Jacobson, Kenneth A.; Shainberg, Asher
Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2685 - 2696
反应条件
in N,N-dimethyl-formamide
T=140°C; 2.5 h; Yield given;
参考文献
Fischer, Bilha; Yefidoff, Revital; Major, Dan T.; Rutman-Halili, Irit; Shneyvays, Valadimir; Zinman, Tova; Jacobson, Kenneth A.; Shainberg, Asher
Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2685 - 2696
参考文献
Gilliard; Monnet et Cartier
Patent: DE343323 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 912
反应条件
1: dimethylformamide / 2.5 h / 140 °C
2: 46 percent / AgNO3, bis(tributyltin)oxide / dimethylformamide / 120 h / Ambient temperature
View Scheme
参考文献
Fischer, Bilha; Yefidoff, Revital; Major, Dan T.; Rutman-Halili, Irit; Shneyvays, Valadimir; Zinman, Tova; Jacobson, Kenneth A.; Shainberg, Asher
Journal of Medicinal Chemistry, 1999 , vol. 42, # 14 p. 2685 - 2696
