triethylamine in 1,4-dioxane RefluxCombinatorial reaction / High throughput screening (HTS);

sodium acetate in ethanol 4 h; Heating;

in 1,2,3,4-tetrahydro-naphthalene Cyclization; Heating;

1: Et3N, cyanuric chloride / CH2Cl2 / < 0 deg C 2: 84 percent / CHCl3 / Heating View Scheme

1: 50 percent / acetone / -5 °C 2: Et3N, cyanuric chloride / CH2Cl2 / < 0 deg C 3: 84 percent / CHCl3 / Heating View Scheme

1.1: phosphorus tribromide / chloroform / 0.67 h / 20 °C / |Inert atmosphere; |Cooling with ice 1.2: 12 h / 20 °C / |Inert atmosphere 2.1: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; caesium carbonate / N,N-dimethyl-formamide / 0.13 h / 140 °C / |Microwave irradiation; |Inert atmosphere View Scheme

piperidine; ethanol

暂无反应条件数据

暂无反应条件数据

palladium on activated charcoal T=285°C;