2,2-二甲氧基丙酸甲酯合成路线 （共 25 条）
反应条件
sulfuric acid in methanol 5 h; Heating;
参考文献
Wenkert, Ernest; Alonso, Miguel E.; Buckwalter, Brian L.; Sanchez, Eduardo L.
Journal of the American Chemical Society, 1983 , vol. 105, # 7 p. 2021 - 2029
反应条件
1: With toluene-4-sulfonic acid in methanol T=58°C; 10 h; 2: With sodium methylate in methanol pH=7;
参考文献
KANSAI PAINT CO., LTD.
Patent: WO2006/35915 A1, 2006 ;
Location in patent: Page/Page column 49-50 ;
反应条件
sulfuric acid 4 h; Reflux;
参考文献
SCHERING CORPORATION
Patent: WO2009/105500 A1, 2009 ;
Location in patent: Page/Page column 215 ;
WO 2009/105500 A1
反应条件
sodium methylate; trimethyl orthoformate in methanol
反应条件
sulfuric acid in methanol 72 h; Ambient temperature;
参考文献
Bowman, Ralph E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 8 p. 1897 - 1904
反应条件
chloro-trimethyl-silane T=22°C;
参考文献
Brook, Michael A.; Chan, T. H.
Synthesis, 1983 , # 3 p. 201 - 203
反应条件
chloro-trimethyl-silane 18 h; Ambient temperature;
参考文献
Brook, Michael A.; Chan, T. H.
Synthesis, 1983 , # 3 p. 201 - 203
反应条件
hydrogenchloride T=0°C;
参考文献
Journal of the Chemical Society, , p. 1033
反应条件
toluene-4-sulfonic acid
参考文献
Journal of Organic Chemistry, , vol. 32, p. 1615 - 1617
反应条件
sealed tube in decane T=200°C; 16 h; secondary products identified;
参考文献
Tetrahedron Letters, , vol. 26, # 16 p. 1931 - 1934
