6-羟基-2,4,5-三氨基嘧啶合成路线

Pfleiderer
Chemische Berichte, 1957 , vol. 90, p. 2631,2633,2635
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Albert; Wood
Journal of Applied Chemistry, 1952 , vol. 2, p. 591
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Winthrop Chem.Co.
Patent: US2345215 , 1941 ;

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Purrmann
Patent: DE721930 , 1940 ;
DRP/DRBP Org.Chem.
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Purrmann
Justus Liebigs Annalen der Chemie, 1940 , vol. 544, p. 188
Justus Liebigs Annalen der Chemie, 1941 , vol. 546, p. 100

1004-75-76-羟基-2,4,5-三氨基嘧啶+

116140-94-4

→

948-60-7蝶呤-6-羧酸

参考文献

Mowat et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 14,18

1004-75-76-羟基-2,4,5-三氨基嘧啶+

4271-30-1N-(4-氨基苯甲酰)-L-谷氨酸

→

2179-16-0(2S)-2-[[4-[1-(2-氨基-4-氧代-1H-蝶啶-6-基)乙基氨基]苯甲酰基]氨基]戊二酸

参考文献

Hultquist et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 619,621.

23588-52-5+

1004-75-76-羟基-2,4,5-三氨基嘧啶

→

25716-33-02-氨基-7-乙基-4(1H)-蝶啶酮

参考文献

Zav'yalov, S. I.; Zavozin, A. G.; Ezhova, G. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 11 p. 2183 - 2185
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 11 p. 2626 - 2628

1004-75-76-羟基-2,4,5-三氨基嘧啶+

631-23-22,2-二羟基丙二酸 1,3-二乙酯

→

2757-91-7+

3254-85-1

参考文献

Taylor; Loux
Journal of the American Chemical Society, 1959 , vol. 81, p. 2474,2478
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Purrmann
Justus Liebigs Annalen der Chemie, 1941 , vol. 548, p. 284,286,290
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Taylor; Abdulla
Tetrahedron Letters, 1973 , p. 2093

1004-75-76-羟基-2,4,5-三氨基嘧啶+

3237-50-15,5-二羟基六氢嘧啶-2,4,6-三酮

→

2757-91-7+

3254-85-1

参考文献

Taylor; Loux
Journal of the American Chemical Society, 1959 , vol. 81, p. 2474,2478

1004-75-76-羟基-2,4,5-三氨基嘧啶+

5221-17-02,3-二溴丙醛+

52980-68-4N-[4-(甲基氨基)苯甲酰基]-L-谷氨酸

→

2410-93-72-[[4-[(2-氨基-4-氧代-1H-蝶啶-6-基)甲基-甲基氨基]苯甲酰基]氨基]戊烷二酸

参考文献

Cosulich; Smith
Journal of the American Chemical Society, 1948 , vol. 70, p. 1922,1925