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| CAS号 : | 872-49-1 |
精确质量 : | 116.01400 |
| 分子式 : | C4H5ClN2 |
logP : | 1.07350 |
| 分子量 : | 116.54900 |
PSA : | 17.82000 |
5-氯-1-甲基咪唑 | |
5-Chloro-1-Methylimidazole | |
872-49-1 | |
C4H5ClN2 | |
116.54900 | |
17.82000 | |
1.07350 | |
116.01400 |
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n20/D 1.511(lit.)
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白色结晶粉末
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205 °F
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82-85 °C11 mm Hg(lit.)
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82-85°C(11 mmHg)
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1.25 g/mL at 25 °C(lit.)
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insoluble
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Stable at room temperature in closed containers under normal storage and handling conditions.
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Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
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3
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S26-S37/39
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2933290090
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Xi
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R36/37/38
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2933990090
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2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% | |
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
由乙二酰二甲胺和五氯化磷反应得到。将过量的乙二酰二甲胺和五氯化磷分次投入反应锅中,在70-80℃下保温2h,放置过夜,减压蒸出氧氯化磷,温度不超过100℃,冷却,加入冰水,搅拌,用30-40%碱液调节pH为9-10,静置。分出油状物,母液冷却,析出无机盐后过滤,用氯仿洗涤,并用氯仿抽提母液。合并油层及氯仿层,回收氯仿,减压蒸馏,收集沸点110-115℃(4.0kPa)馏分,得1-甲基-5-氯咪唑。收率为52%。 | |
医药中间体。 |
