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| CAS号 : | 60-93-5 |
精确质量 : | 396.13700 |
| 分子式 : | C20H26Cl2N2O2 |
logP : | 4.71510 |
| 分子量 : | 397.33900 |
PSA : | 45.59000 |
盐酸奎宁 | |
Quinine dihydrochloride | |
60-93-5 | |
C20H26Cl2N2O2 | |
397.33900 | |
45.59000 | |
4.71510 | |
396.13700 |
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白色固体
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253.7ºC
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495.9ºC at 760 mmHg
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238-2400C
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Stable, but may be light sensitive. Efflorescent. Incompatible with strong oxidizing agents.
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6.1(b)
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S26; S36
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III
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1544
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2939200000
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Xi
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R36/37/38
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2933990090
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2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% | |
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
奎宁是喹啉类衍生物，能与疟原虫的DNA结合，形成复合物，抑制DNA的复制和RNA的转录，从而抑制原虫的蛋白合成，作用较氯奎为弱。另外，奎宁能降低疟原虫氧耗量，抑制疟原虫内的磷酸化酶而干扰其糖代谢。 |
