3-溴代苯乙酮

3-溴代苯乙酮

1-(3-bromophenyl)ethanone

2142-63-4

C8H7BrO

199.04500

17.07000

2.65170

197.96800

n20/D 1.576(lit.)

透明黄色液体

>230 °F

79-81 °C0.2 mm Hg

8-11 °C(lit.)

1.505 g/mL at 25 °C(lit.)

0.0165mmHg at 25°C

Stable at room temperature in closed containers under normal storage and handling conditions.

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

3

29147090

S26-S36-S24/25

II; III

Xi

R36/38

2933990090

2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

<p>将40g(0.3mol)间氨基苯乙酮、122mL36%氢溴酸和水120mL的混合溶液,用21.2g(0.31mol)亚硝酸钠和36mL水的溶液在0℃以下重氮化。另在54.2g硫酸铜、27.2g溴化钾和250mL水的溶液中,通入二氧化硫至完全还原。将溴化亚铜溶液加入重氮盐溶液中,然后置于水浴上加热片刻,水蒸气蒸馏。用乙醚从馏出液内萃取间溴苯乙酮,再用稀碱、稀酸及水洗涤乙醚溶液。干燥后蒸馏,得产品。沸点131℃(2.13kPa)。</p>

<p>用作有机合成原料,也是合成软化血管类药物的中间体</p>