1: diethyl ether View Scheme

byproducts: (C4H9O)2BCCCHCH2; at room temp.;;

Grignard-reagent

暂无反应条件数据

1: diethyl ether 4: ammonia View Scheme

1: n-butyllithium / diethyl ether 2: I2 View Scheme

n-butyllithium in diethyl ether at -40°C;;

2: ammonia 3: I2 View Scheme

hydrogenchloride; aluminium trichloride in dichloromethane AlCl3 catalyst added to a soln. of BrCN in CH2Cl2 under N2; obtained soln. added dropwise to a soln. of 1-triethylstannylbut-3-ene-1-yne at 0 ° C; after stirring for 30 min mixture poured into ice cold HCl soln.; organic layer washed with water and dried over MgSO4; after removal of solvent residue distilled to yield 1-cyanobut-3-ene-1-yne; IR, H-NMR;

sodium in diethyl ether byproducts: sodium vinylacetylenide; the soln. of stannane was added to a suspn. of Na, the mixt. was stirred, filtered under N2; the product was sepd. from filtrate by distn.;