7-硝基-1,2,3,4-四氢异喹啉盐酸盐合成路线

ABBOTT LABORATORIES; CLARK, Richard, F.; BELL, Randy, L.; BA-MAUNG, Nwe, Y.; ERICKSON, Scott, A.; FIDANZE, Steve, D.; MANTEI, Robert, A.; SHEPPARD, George, S.; SORENSEN, Bryan, K.; WANG, Gary, T.; WANG, Jieyi
Patent: WO2010/138576 A1, 2010 ;
Location in patent: Page/Page column 104 ;
WO 2010/138576 A1

99365-69-27-硝基-1,2,3,4-四氢异喹啉盐酸盐

72299-68-47-氨基-1,2,3,4-四氢异喹啉

参考文献

Grunewald, Gary L.; Dahanukar, Vilas H.; Caldwell, Timothy M.; Criscione, Kevin R.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 25 p. 3997 - 4005

99365-69-27-硝基-1,2,3,4-四氢异喹啉盐酸盐

244219-96-31,7-异喹啉二胺

参考文献

Gutteridge, Clare E.; Hoffman, Marshall M.; Bhattacharjee, Apurba K.; Milhous, Wilbur K.; Gerena, Lucia
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 2 p. 786 - 789

99365-69-27-硝基-1,2,3,4-四氢异喹啉盐酸盐

13058-73-67-硝基异喹啉

参考文献

Deiters, Emmanuel; Song, Bo; Chauvin, Anne-Sophie; Vandevyver, Caroline D. B.; Gumy, Frederic; Buenzli, Jean-Claude G.
Chemistry - A European Journal, 2009 , vol. 15, # 4 p. 885 - 900

24424-99-5二碳酸二叔丁酯+

99365-69-27-硝基-1,2,3,4-四氢异喹啉盐酸盐

171049-42-67-硝基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯

参考文献

ARRAY BIOPHARMA INC.
Patent: WO2009/158426 A1, 2009 ;
Location in patent: Page/Page column 108 ;
WO 2009/158426 A1