2-甲基-4-硝基苯酚合成路线

参考文献

AKZO NOBEL N.V.; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2006/95014 A1, 2006 ;
Location in patent: Page/Page column 33 ;
WO 2006/095014 A1

99-53-62-甲基-4-硝基苯酚+

77-78-1硫酸二甲酯

50741-92-92-甲基-4-硝基苯甲醚

参考文献

JAMES BLACK FOUNDATION
Patent: WO2007/135417 A1, 2007 ;
Location in patent: Page/Page column 63 ;
WO 2007/135417 A1

186581-53-3重氮甲烷+

99-53-62-甲基-4-硝基苯酚

50741-92-92-甲基-4-硝基苯甲醚

参考文献

Nojima; Kawaguchi; Ohya; et al.
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 1047 - 1051

99-53-62-甲基-4-硝基苯酚

2835-96-32-甲基-4-氨基苯酚

参考文献

Menard, Delphine; Niculescu-Duvaz, Ion; Dijkstra, Harmen P.; Niculescu-Duvaz, Dan; Suijkerbuijk, Bart M. J. M.; Zambon, Alfonso; Nourry, Arnaud; Roman, Esteban; Davies, Lawrence; Manne, Helen A.; Friedlos, Frank; Kirk, Ruth; Whittaker, Steven; Gill, Adrian; Taylor, Richard D.; Marais, Richard; Springer, Caroline J.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 13 p. 3881 - 3891

99-53-62-甲基-4-硝基苯酚

534-52-1二硝酚

参考文献

Robinson
Journal of the Chemical Society, 1916 , vol. 109, p. 1087

99-53-62-甲基-4-硝基苯酚

136-90-34-甲氧基-3-甲基苯胺

参考文献

Baliah,V.; Kanagasabapathy,V.M.
Tetrahedron, 1978 , vol. 34, p. 3611 - 3615

99-53-62-甲基-4-硝基苯酚+

109384-19-2N-Boc-4-羟基哌啶

138227-68-61N-BOC4-(2-甲基-4-硝基苯氧基)哌啶

参考文献

Chemical and Pharmaceutical Bulletin, , vol. 56, # 6 p. 758 - 770

99-53-62-甲基-4-硝基苯酚

1570-64-54-氯-2-甲基苯酚

参考文献

Fujio,M. et al.
Bulletin of the Chemical Society of Japan, 1975 , vol. 48, p. 2127 - 2133

99-53-62-甲基-4-硝基苯酚

183945-52-02-甲基-4-氨基-1-三氟甲氧基-苯

参考文献

Kuo, Elizabeth A.; Hambleton, Philip T.; Kay, David P.; Evans, Phillip L.; Matharu, Saroop S.; Little, Edward; McDowall, Neil; Jones, C. Beth; Hedgecock, Charles J. R.; Yea, Christopher M.; Chan, A. W. Edith; Hairsine, Peter W.; Ager, Ian R.; Tully, W. Roger; Williamson, Richard A.; Westwood, Robert
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4608 - 4621

99-53-62-甲基-4-硝基苯酚

29027-13-22-甲基-4,6-二硝基苯甲醚

参考文献

Robinson
Journal of the Chemical Society, 1916 , vol. 109, p. 1087