5-氨基间苯二甲酸二甲酯合成路线 （共 29 条）
参考文献
Journal of the Chemical Society, , vol. 87, p. 1265
反应条件
sulfuric acid 24 h; RefluxSolvolysis;
参考文献
Sukul, Pradip K.; Malik, Sudip
RSC Advances, 2013 , vol. 3, # 6 p. 1902 - 1915
反应条件
1: hydrogen chloride 2: ammonium sulfide View Scheme
参考文献
Journal of the Chemical Society, , vol. 87, p. 1265
反应条件
1: HNO3; H2SO4; SO3 2: iron-powder; aqueous HCl View Scheme
反应条件
ethanol; hydrogen sulfide; ammonia
参考文献
Journal of the Chemical Society, , vol. 87, p. 1265
反应条件
hydrogen; acetic acid in N-methyl-acetamide; sodium hydrogencarbonate; N,N-dimethyl-formamide
参考文献
American Hospital Supply Corporation
Patent: US4275153 A1, 1981 ;
反应条件
1: With hydrogen bromide; sodium nitrite in water T=5°C; 2: With copper(I) bromide in water T=5 - 20°C;
参考文献
Liao, Teng-Biao; Ling, Yun; Chen, Zhen-Xia; Zhou, Ya-Ming; Weng, Lin-Hong
Chemical Communications, 2010 , vol. 46, # 7 p. 1100 - 1102
反应条件
1: With hydrogenchloride; sodium nitrite in water T=-5°C; 0.25 h; 2: With hydrofluoroboric acid in water T=0°C; 0.5 h; 3: T=110°C;
参考文献
ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.
Patent: WO2004/14881 A2, 2004 ;
Location in patent: Page 100-101 ;
WO 2004/014881 A2
反应条件
1: 49 percent / sodium nitrite; aq. HCl; KI / H2O; toluene / 13 h 2: potassium acetate; PdCl2(dppf) / dimethylformamide / 2 h / 80 °C 3: PdCl2(dppf); CsF / dimethylformamide; H2O / 12 h / 80 °C 4: 89 percent / NaOH / tetrahydrofuran; H2O / 1 h / Heating View Scheme
参考文献
Mazik, Monika; Koenig, Alexander
Journal of Organic Chemistry, 2006 , vol. 71, # 20 p. 7854 - 7857
反应条件
1: 96 percent / LiAlH4 / tetrahydrofuran / 14 h / Heating 2: 90 percent / Et3N / tetrahydrofuran / 3 h / 20 °C 3: 87 percent / SOCl2; pyridine / CH2Cl2 / 12 h / 20 °C View Scheme
参考文献
Yu, Kunquan; Sommer, William; Richardson, John M.; Weck, Marcus; Jones, Christopher W.
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 1 p. 161 - 171
