1: 70 percent / K2CO3 / 0.17 h / 170 - 180 °C 2: 92 percent / K2CO3 / diethyl ether; acetone / 20 °C 3: 80 percent aq. AcOH / 5 h / 108 °C 4: aq. KOH / methanol / 36 h / 55 °C View Scheme

Na2B4O7; sodium hydroxide in water

sodium hydroxide; borax; dimethyl sulfate

sodium hydroxide; borax; sulfuric acid; dimethyl sulfate in water

sodium hydroxide; sulfuric acid; Na2B4O7 in water

sodium hydroxide; B4H2O7(2-)*2Na(1+) in water T=20°C; 5 h;

1.1: K2CO3 / dimethylformamide / 1 h / 85 °C 1.2: 76 percent / dimethylformamide / 24 h / 20 °C 2.1: 95 percent / K2CO3 / dimethylformamide / 1.5 h / 150 °C 3.1: 96 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / 60 °C 4.1: 96 percent / pyridinium chlorochromate / tetrahydrofuran / 3 h / 20 °C 5.1: dioxane / 24 h / 20 °C 5.2: 64 percent / HCl / dioxane / 24 h / 20 °C 6.1: 94 percent / pyridine / 0.25 h / 0 °C 7.1: 61 percent / phenyliodine(III) bis(trifluoroacetate) / 2,2,2-trifluoro-ethanol / 0.17 h / -40 °C 8.1: 95 percent / BCl3 / CH2Cl2 / 20 h / -78 °C 9.1: 83 percent / pyridine / 3 h / 0 °C 10.1: 98 percent / formic acid; Et3N; PPh3 / Pd(OAc)2 / dimethylformamide / 72 h / 60 °C 11.1: 78 percent / lithium tri-sec-butylborohydride / tetrahydrofuran / 3 h / -78 °C 12.1: 96 percent / TBAB; KOH / methanol / 24 h / 80 °C 13.1: NaBH4 / methanol / 24 h / 20 °C View Scheme

1: 83 percent / 180 °C 2: 97 percent / aq. LiOH / methanol / Heating View Scheme

anschl. mit wss. NaOH;

1: 175 °C 2: K2CO3 / acetone / 50 °C 3: aq. AcOH / Heating View Scheme