N-Boc-3-哌啶酮合成路线

参考文献

Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
Patent: EP2241569 A1, 2010 ;
Location in patent: Page/Page column 28-29 ;

98977-36-7N-Boc-3-哌啶酮

276872-89-01-叔丁氧羰基-3-亚甲基哌啶

参考文献

RANBAXY LABORATORIES LIMITED
Patent: WO2006/85212 A2, 2006 ;
Location in patent: Page/Page column 44 ;

1779-49-3甲基三苯基溴化膦+

98977-36-7N-Boc-3-哌啶酮

276872-89-01-叔丁氧羰基-3-亚甲基哌啶

参考文献

Dallanoce, Clelia; Frigerio, Fabio; Grazioso, Giovanni; Matera, Carlo; Visconti, Giacomo Luca; De Amici, Marco; Pucci, Luca; Pistillo, Francesco; Fucile, Sergio; Gotti, Cecilia; Clementi, Francesco; De Micheli, Carlo
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 12 p. 5790 - 5799

98977-36-7N-Boc-3-哌啶酮+

765-30-0环丙胺

887588-04-73-(环丙基氨基)哌啶-1-甲酸叔丁酯

参考文献

WO2007/110449 A1, ;

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WO 2007/110449 A1

98977-36-7N-Boc-3-哌啶酮+

75-31-0异丙胺

1282742-29-33-异丙基氨基-哌啶-1-羧酸叔丁酯

参考文献

BIOGEN IDEC MA INC.; SUNESIS PHARMACEUTICALS, INC.; HOPKINS, Brian, T.; SCOTT, Daniel; CONLON, Patrick; JENKINS, Tracy, J.; POWELL, Noel; GUAN, Bing; CURERVO, Julio, H.; WANG, Deping; TAVERAS, Art
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WO 2012/058645 A1

98977-36-7N-Boc-3-哌啶酮

1008779-94-93-羟基哌啶-3-羧酸甲酯

参考文献

MITHRIDION, INC.; ABRAHAM, Brent, D.; COPP, Richard, R.; FARNHAM, James, G.; HANSON, Seth, A.; HENDRICKSON, Michael, L.; OCKULY, Jeffrey, C.; TWOSE, Trevor, M.; VERDONE, Melinda, L.
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WO 2011/085406 A1
Title/Abstract Full Text Show Details
MITHRIDION, INC.; ABRAHAM, Brent, D.; COPP, Richard, R.; FARNHAM, James, G.; HANSON, Seth, A.; HENDRICKSON, Michael, L.; OCKULY, Jeffrey, C.; TWOSE, Trevor, M.; VERDONE, Melinda, L.
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WO 2012/033956 A1

98977-36-7N-Boc-3-哌啶酮

1219832-36-63-氨基甲基-3-氟哌啶-1-羧酸叔丁酯

参考文献

HUTCHISON MEDIPHARMA LIMITED; Su, Wei-Guo; Deng, Wei; Ji, Jianguo
Patent: US2014/121200 A1, 2014 ;

98977-36-7N-Boc-3-哌啶酮

136423-06-83-(苯基甲基)-1-哌啶羧酸 1,1-二甲基乙酯

参考文献

Varnes, Jeffrey G.; Gardner, Daniel S.; Santella III, Joseph B.; Duncia, John V.; Estrella, Melissa; Watson, Paul S.; Clark, Cheryl M.; Ko, Soo S.; Welch, Patricia; Covington, Maryanne; Stowell, Nicole; Wadman, Eric; Davies, Paul; Solomon, Kimberley; Newton, Robert C.; Trainor, George L.; Decicco, Carl P.; Wacker, Dean A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 7 p. 1645 - 1649

98977-36-7N-Boc-3-哌啶酮

31251-28-23-(哌啶-3-基)吡啶

参考文献

Wang, Xueqing; Bhatia, Pramila A.; Daanen, Jerome F.; Latsaw, Steve P.; Rohde, Jeffrey; Kolasa, Teodozyi; Hakeem, Ahmed A.; Matulenko, Mark A.; Nakane, Masaki; Uchic, Marie E.; Miller, Loan N.; Chang, Renjie; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 15 p. 4667 - 4678

98977-36-7N-Boc-3-哌啶酮+

105-56-6氰乙酸乙酯

193537-14-32-氨基-4,7-二氢-5H-噻吩并[2,3-c]吡啶-3,6-二甲酸 6-叔丁酯 3-乙酯

参考文献

Nakhi, Ali; Adepu, Raju; Rambabu; Kishore, Ravada; Vanaja; Kalle, Arunasree M.; Pal, Manojit
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4418 - 4427