(1S)-1-(2R)-环氧乙基-2-苯乙基氨基甲酸叔丁酯合成路线 （共 74 条）
反应条件
1: Li / tetrahydrofuran / -55 °C 2: 97 percent / H2 / Pd(OH)2/C / 760 Torr 3: Et3N 4: KOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 11 p. 3440 - 3448
反应条件
1: 99 percent / pyridine*SO3, DMSO, Et3N / 10 °C 2: Li / tetrahydrofuran / -55 °C 3: 97 percent / H2 / Pd(OH)2/C / 760 Torr 4: Et3N 5: KOH / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 11 p. 3440 - 3448
反应条件
1: 7.8 g / NaBH4 / toluene; ethanol / 8 h / -78 - 0 °C 2: 89 percent / KOH / ethanol / 2 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 21 p. 7344 - 7347
反应条件
1: Ti(O-i-Pr)2(N3)2 / benzene / Heating 2: H2 / Pd/C / ethyl acetate / 20 °C 3: Ph3P; diisopropyl azodicarboxylate / CHCl3 / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5075 - 5083
反应条件
1: H2 / Pd/C / ethyl acetate / 20 °C 2: Ph3P; diisopropyl azodicarboxylate / CHCl3 / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5075 - 5083
反应条件
1: CH2Cl2 / 3 h / 23 °C 2: 356 mg / H2 / Pd(OH)2 / ethyl acetate; methanol / 12 h 3: 61 percent / PPh3, DEAD / CHCl3 / 72 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 18 p. 6146 - 6152
反应条件
1: KOH / ethanol; H2O / 17 h / Heating 2: CH2Cl2 / 3 h / 23 °C 3: 356 mg / H2 / Pd(OH)2 / ethyl acetate; methanol / 12 h 4: 61 percent / PPh3, DEAD / CHCl3 / 72 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 18 p. 6146 - 6152
反应条件
1: 356 mg / H2 / Pd(OH)2 / ethyl acetate; methanol / 12 h 2: 61 percent / PPh3, DEAD / CHCl3 / 72 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 18 p. 6146 - 6152
反应条件
1: Ti(O-i-Pr)4; D(-)-DIPT; t-BuOOH / CH2Cl2 / -20 °C 2: Ti(O-i-Pr)2(N3)2 / benzene / Heating 3: H2 / Pd/C / ethyl acetate / 20 °C 4: Ph3P; diisopropyl azodicarboxylate / CHCl3 / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5075 - 5083
反应条件
1.1: p-TsOH*H2O / CH2Cl2 2.1: NaH / tetrahydrofuran 3.1: CuBr*SMe2 / tetrahydrofuran 4.1: p-TsOH*H2O 4.2: KOH / methanol View Scheme
参考文献
Organic letters, , vol. 3, # 15 p. 2349 - 2351
