(R)-5-溴甲基-2-吡咯烷酮合成路线 （共 5 条）
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane 1.5 h; Ambient temperature;
参考文献
Ackermann, Jean; Matthes, Michael; Tamm, Christoph
Helvetica Chimica Acta, 1990 , vol. 73, # 1 p. 122 - 132
反应条件
1: H2O / 63 h / Heating 2: SOCl2 / 48 h / Ambient temperature; pH=0 3: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 4: 77 percent / CBr4, PPh3 / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 1 p. 122 - 132
反应条件
1: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 2: 77 percent / CBr4, PPh3 / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 1 p. 122 - 132
反应条件
1: SOCl2 / 48 h / Ambient temperature; pH=0 2: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 3: 77 percent / CBr4, PPh3 / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 1 p. 122 - 132
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene T=80°C; 4 h;
参考文献
Mandal, Amit K.; Hines, John; Kuramochi, Kouji; Crews, Craig M.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 18 p. 4043 - 4047
