甲基 3-氯-5-羟基苯甲酸合成路线 （共 6 条）
反应条件
sulfuric acid
5.5 h; Heating / reflux;
参考文献
Old, David W.; Gac, Todd S.; Ngo, Vinh X.
Patent: US2007/265464 A1, 2007 ;
Location in patent: Page/Page column 45 ;
反应条件
Oxonereg; in acetone
T=25°C; 0.116667 h;
参考文献
Maleczka Jr., Robert E.; Shi, Feng; Holmes, Daniel; Smith III, Milton R.
Journal of the American Chemical Society, 2003 , vol. 125, # 26 p. 7792 - 7793
反应条件
boron tribromide in dichloromethane
T=0°C; 3 h;
参考文献
Takahashi, Kimio; Shimizu, Sumio; Ogata, Masaru
Heterocycles, 1985 , vol. 23, # 6 p. 1483 - 1491
反应条件
1: 1,2-bis(dimethylphosphino)ethane; (indenyl)Ir(1,5-cyclooctadiene) / 3 h / 150 °C
2: aq. oxone / acetone / 0.12 h / 25 °C
View Scheme
参考文献
Maleczka Jr., Robert E.; Shi, Feng; Holmes, Daniel; Smith III, Milton R.
Journal of the American Chemical Society, 2003 , vol. 125, # 26 p. 7792 - 7793
反应条件
1: hexamethylphosphoramide / 15 h / 115 - 120 °C
2: 70 percent / acetyl chloride / 15 h / Ambient temperature
3: 93 percent / BBr3 / CH2Cl2 / 3 h / 0 °C
View Scheme
参考文献
Takahashi, Kimio; Shimizu, Sumio; Ogata, Masaru
Heterocycles, 1985 , vol. 23, # 6 p. 1483 - 1491
反应条件
1: 70 percent / acetyl chloride / 15 h / Ambient temperature
2: 93 percent / BBr3 / CH2Cl2 / 3 h / 0 °C
View Scheme
参考文献
Takahashi, Kimio; Shimizu, Sumio; Ogata, Masaru
Heterocycles, 1985 , vol. 23, # 6 p. 1483 - 1491
