4,6-二氯-2-吡啶甲酸甲酯合成路线 (共 8 条)
反应条件
thionyl chloride; sodium iodide 1.) 76 h, 2.) r.t., 0.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Organic Preparations and Procedures International, , vol. 29, # 1 p. 117 - 122
反应条件
1: aqueous ethylamine 2: SOCl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 23, p. 1030
反应条件
1: SOCl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 23, p. 1030
反应条件
1: SOCl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 23, p. 1030
参考文献
Journal of Organic Chemistry, , vol. 23, p. 1030
反应条件
thionyl chloride; N,N-dimethyl-formamide 1) 40-45 deg C, 45 min; 45->72 deg C, 2 h; 72 deg C, 21 h, 2) toluene, room temperature, 1 h; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 26, # 10 p. 2017 - 2025
反应条件
sodium hydroxide in ethanol; water
参考文献
Kureha Kagaku Kogyo K.K.
Patent: US6610853 B1, 2003 ;
反应条件
ammonium chloride; diisobutylaluminium hydride in water; toluene
参考文献
Merck and Co., Inc.
Patent: US5750549 A1, 1998 ;
US 5750549 A