1: methyl-2-amino-4-methyl-pentanoate With Alcalase; water in tert-butyl alcohol T=25°C; kinetic resolution; pH=8.5; 2: p-methoxybenzyloxycarbonyl-Phe-OMe With Alcalase in tert-butyl alcohol Condensation;

1: D,L-Ala-O(nPr) With Alcalase; water in tert-butyl alcohol T=25°C; kinetic resolution; pH=8.5; 2: p-methoxybenzyloxycarbonyl-Phe-OMe With Alcalase in tert-butyl alcohol Condensation;