5-(2-溴甲基)-2,2-二甲基-1,3-二氧六环合成路线

102147-75-1→97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环

参考文献

Zheng, Qi-Huang; Wang, Ji-Quan; Liu, Xuan; Fei, Xiangshu; Mock, Bruce H.; Glick-Wilson, Barbara E.; Sullivan, Michael L.; Raikwar, Sudhanshu P.; Gardner, Thomas A.; Kao, Chinghai; Hutchins, Gary D.
Synthetic Communications, 2004 , vol. 34, # 4 p. 689 - 704

558-13-4四溴化碳+102147-75-1+603-35-0三苯基磷→

参考文献

BEECHAM GROUP PLC
Patent: EP141927 B1, 1991 ;

7459-46-31,1,2-乙烷三甲酸三乙酯→97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环

参考文献

Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, p. S112 - S112

6482-32-22-羟甲基-1,4-丁二醇→97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环

参考文献

Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, p. S112 - S112

558-13-4四溴化碳+102147-75-1+603-35-0三苯基磷→97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环

参考文献

BEECHAM GROUP PLC
Patent: EP141927 B1, 1991 ;

97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环→39809-25-19-[4-羟基-3-(羟甲基)-丁基]-鸟嘌呤

参考文献

Wang, Ji-Quan; Zheng, Qi-Huang; Fei, Xiangshu; Mock, Bruce H.; Hutchins, Gary D.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 3933 - 3938

97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环→206067-84-76H-嘌呤-6-酮

参考文献

Wang, Ji-Quan; Zheng, Qi-Huang; Fei, Xiangshu; Mock, Bruce H.; Hutchins, Gary D.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 3933 - 3938

97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环→104227-86-32-[2-(2-氨基-9h-嘌呤-9-基)乙基]-1,3-丙二醇

参考文献

Journal of Medicinal Chemistry, , vol. 30, # 9 p. 1636 - 1642

97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环+10310-21-12-氨基-6-氯嘌呤→97845-59-5

参考文献

Harnden, M.R.; Jarvest, R.L.
Tetrahedron Letters, 1985 , vol. 26, # 35 p. 4265 - 4268

97845-58-45-(2-溴甲基)-2,2-二甲基-1,3-二氧六环+10310-21-12-氨基-6-氯嘌呤→97845-59-5

参考文献

Zheng, Qi-Huang; Wang, Ji-Quan; Liu, Xuan; Fei, Xiangshu; Mock, Bruce H.; Glick-Wilson, Barbara E.; Sullivan, Michael L.; Raikwar, Sudhanshu P.; Gardner, Thomas A.; Kao, Chinghai; Hutchins, Gary D.
Synthetic Communications, 2004 , vol. 34, # 4 p. 689 - 704