2-(2-噻吩基)苯甲酰氯合成路线 （共 5 条）
反应条件
in diethyl ether T=0°C;
参考文献
Storflor, Harry; Skramstad, Jan
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 3 p. 178 - 183
反应条件
thionyl chloride
4 h; Ambient temperature;
参考文献
Storflor, Harry; Skramstad, Jan
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 3 p. 178 - 183
反应条件
1: 1.) Mg / 1) THF, 80 deg C, 45 min; 2) diethyl ether
2: 77 percent / thionyl chloride / 4 h / Ambient temperature
View Scheme
参考文献
Storflor, Harry; Skramstad, Jan
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 3 p. 178 - 183
反应条件
1: 67 percent / isoamyl nitrite / 0.5 h / 60 °C
2: 1.) Mg / 1) THF, 80 deg C, 45 min; 2) diethyl ether
3: 77 percent / thionyl chloride / 4 h / Ambient temperature
View Scheme
参考文献
Storflor, Harry; Skramstad, Jan
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 3 p. 178 - 183
反应条件
tin(IV) chloride in benzene
T=0 - 10°C; Intramolecular Friedel-Crafts acylation; 0.5 h; Inert atmosphere;
参考文献
Pouchain, Laurent; Aleveque, Olivier; Nicolas, Yohann; Oger, Agathe; Regent, Charles-Henri Le; Allain, Magali; Blanchard, Philippe; Roncali, Jean
Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 1054 - 1064
