2-脱氧-2-氟-1,3,5-三苯甲酰基-alpha-D-阿拉伯呋喃糖合成路线 (共 18 条)
反应条件
[bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane T=50°C;
参考文献
Nucleosides, nucleotides and nucleic acids, , vol. 22, # 5-8 p. 1343 - 1346
反应条件
triethylamine tris(hydrogen fluoride) in ethyl acetate T=60 - 70°C; 4.5 h;
参考文献
EP2177527 A1, ;
Page/Page column 11-12 ;
反应条件
triethylamine tris(hydrogen fluoride) in ethyl acetate T=80°C; Substitution; 24 h;
参考文献
Tetrahedron, , vol. 54, # 28 p. 8223 - 8240
反应条件
KHF2; hydrogen fluoride in various solvent(s) T=160°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 50, # 19 p. 3644 - 3647
反应条件
triethylamine tris(hydrogen fluoride) in ethyl acetate T=70°C; Yield given;
参考文献
Tetrahedron Letters, , vol. 37, # 1 p. 17 - 20
反应条件
tetrabutyl ammonium fluoride in ethyl acetate T=71 - 72°C; Substitution; 0.333333 h;
参考文献
Journal of Fluorine Chemistry, , vol. 106, # 1 p. 87 - 91
反应条件
hydrogen fluoride; triethylamine in ethyl acetate T=71 - 72°C; Substitution; 4 h; Product distribution; Further Variations:ReagentsSolventsreaction time;
参考文献
Journal of Fluorine Chemistry, , vol. 106, # 1 p. 87 - 91
反应条件
KHF2; hydrogen fluoride in various solvent(s) T=160°C; 1 h; other reaction conditions; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 50, # 19 p. 3644 - 3647
反应条件
1: 98 percent / HBr / CH2Cl2; acetic acid / 20 h / 20 °C 2: 76.2 percent / CHCl3 / 20 h / Heating 3: 93 percent / liquid ammonia; methanol / 65 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, p. 85 - 88
反应条件
potassium fluoride in various solvent(s) T=95°C; Substitution; 1 h;
参考文献
Bieniarz, Christopher; Behme, Chris; Ramakrishna, Kornepati
Journal of Fluorine Chemistry, 2000 , vol. 106, # 1 p. 99 - 102