16,17-alpha环氧孕烯醇酮合成路线 （共 20 条）
反应条件
sodium hydroxide; urea hydrogen peroxide addition compound in methanol; water T=5°C; 72 h;
参考文献
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Patent: WO2004/60906 A1, 2004 ;
Location in patent: Page/Page column 6 ;
反应条件
tert.-butylhydroperoxide; lithium hydroxide in ethanol 48 h; Ambient temperature;
参考文献
Holland, Herbert L.; Riemland, Elly; Ulrich, Daum
Canadian Journal of Chemistry, 1982 , vol. 60, p. 1919 - 1923
反应条件
methanol; sodium hydroxide; dihydrogen peroxide
参考文献
US2684364 , ;
US2705233 , ;
Journal of the Chemical Society, , p. 958,962
反应条件
benzene Erwaermen des erhaltenen 16α,17-Epoxy-6β-methoxy-3α,5α-cyclo-pregnan-20-ons mit Schwefelsaeure enthaltendem wss.Dioxan;
参考文献
Journal of the American Chemical Society, , vol. 72, p. 367,369
US2686181 , ;
反应条件
1: potassium acetate 2: benzene / Erwaermen des erhaltenen 16α,17-Epoxy-6β-methoxy-3α,5α-cyclo-pregnan-20-ons mit Schwefelsaeure enthaltendem wss.Dioxan View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 367,369
反应条件
sodium hydroxide; dihydrogen peroxide
参考文献
Guo, Chuangxing; Fuchs
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1099 - 1102
反应条件
hydrogen bromide und anschliessenden Hydrieren an Palladium/CaCO3 in Kaliumacetat enthaltendem Methanol;
参考文献
Ringold et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 820,823
反应条件
1: 0.67 g / KOH, iodosobenzene diacetate / 1 h 2: 0.049 g / pyridine / 24 h / 20 °C 3: 0.015 g / p-TsOH / acetone / 20 deg C, 48 h; reflux, 3 h View Scheme
参考文献
Kamernitskii, A. V.; Turuta, A. M.; Istomina, Z. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 8 p. 1716 - 1720
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 8 p. 1887 - 1892
反应条件
2: 63 percent / hydrazine, N,N-dimethylethanolamine 3: xylene / 1 h / Heating 4: 90 percent / xylene / 2.5 h / Heating 5: 96 percent / hydrogen / platinum black / ethyl acetate 6: 84 percent / dilute sulfuric acid 7: 97 percent / Wolff-Kishner reduction View Scheme
参考文献
Tanabe, Masato; Hayashi, Koji
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 862 - 863
