4-(1-羟基乙基)-苯甲酸合成路线 （共 9 条）
反应条件
sodium tetrahydroborate in ethanol
T=20°C; 3 h;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
C20H25N2(1+)*Cl(1-); water; oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=20°C; 14 h; Schlenk technique; chemoselective reaction;
参考文献
Moehlmann, Lennart; Ludwig, Stefan; Blechert, Siegfried
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 602 - 607
反应条件
1: With potassium hydroxide in tetrahydrofuran; methanol; water
T=20°C;
2: With hydrogenchloride in methanol; water
参考文献
MERCK and CO., INC.
Patent: WO2008/10985 A2, 2008 ;
Location in patent: Page/Page column 155 ;
WO 2008/010985 A2
反应条件
dichloro bis(acetonitrile) palladium(II); [Ph4(η5-C4CO)2H(CO)4Ru2](μ-H); water; p-benozquinone in methanol; isopropyl alcohol
T=85°C; 36 h; Inert atmosphereGlovebox; regioselective reaction;
参考文献
Yang, Yongsheng; Guo, Jiayi; Ng, Huimin; Chen, Zhiyong; Teo, Peili
Chemical Communications, 2014 , vol. 50, # 20 p. 2608 - 2611
反应条件
n-butyllithium; diethyl ether
anschliessend Behandeln mit festem Kohlendioxid;
参考文献
Gilman; Melstrom
Journal of the American Chemical Society, 1948 , vol. 70, p. 4177
反应条件
(tetrakis(N-methyl-4-pyridinium)porphyrinato)-manganese(III) phosphotungstate; PhIO
T=30°C; 1 h; Ionic liquid;
参考文献
Liu, Wei; Wan, Qing-Xia; Liu, Ye
Monatshefte fur Chemie, 2010 , vol. 141, # 8 p. 859 - 865
反应条件
cytochrome P450 enzyme CYP199A4 from Rhodopseudomonas palustris HaA2; nicotinamide adenine dinucleotide; bovine liver catalase in ethanol
pH=7.4; Enzymatic reaction;
参考文献
Bell, Stephen G.; Zhou, Ruimin; Yang, Wen; Tan, Adrian B. H.; Gentleman, Alexander S.; Wong, Luet-Lok; Zhou, Weihong
Chemistry - A European Journal, 2012 , vol. 18, # 52 p. 16677 - 16688
参考文献
Reetz, Manfred T.; Westermann, Juergen; Steinbach, Rainer; Wenderoth, Bernd; Peter, Roland; et al.
Chemische Berichte, 1985 , vol. 118, # 4 p. 1421 - 1440
反应条件
1: acetic acid; ozone / Erwaermen des Reaktionsprodukts mit Wasser
2: aqueous sodium carbonate; sodium-amalgam
View Scheme
参考文献
Komppa
Annales Academiae Scientiarum Fennicae, Series A, 1935 , vol. 44, # 9 p. 3,4
