1: K2CO3 / dimethylformamide / 4 h / 75 °C 2: NaOCH3 / methanol / 1.5 h / Heating View Scheme

1: NaH / toluene / 2 h / 75 °C 2: 0.75 g / NaOCH3 / methanol / 0.75 h / Heating View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 58 percent / 1N-HCl / 1.5 h / Heating<br />2: 72 percent / triethylamine / dioxane / 0.33 h / Heating<br />3: 70 percent / 1,3-dibromo-5,5-dimethylhydantoin, benzoyl peroxide / CCl₄ / 0.33 h / Heating; Irradiation<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 51 percent / SnCl₂*2H₂O, conc. HCl / 0.25 h / below 40 deg C<br />2: 58 percent / 1N-HCl / 1.5 h / Heating<br />3: 72 percent / triethylamine / dioxane / 0.33 h / Heating<br />4: 70 percent / 1,3-dibromo-5,5-dimethylhydantoin, benzoyl peroxide / CCl₄ / 0.33 h / Heating; Irradiation<br /> <br /> &nbsp;