20 palladium hydroxide on carbon; hydrogen in tetrahydrofuran; methanol; water T=20°C; 5 h;

lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; 2.5 h; Inert atmosphere;

acetic acid; nickel in ethanol T=50°C; Elimination; desulfurization; 0.5 h;

Diaporthe sp in methanol pH=6.44; 24 h;

1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 4 h / 0 - 40 °C / |Inert atmosphere 2.1: triphenylphosphine / tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere 2.2: 0.42 h / 20 °C / |Inert atmosphere; |Sonication 3.1: triphenylphosphine; gold(III) chloride; silver trifluoromethanesulfonate / dichloromethane / 7 h / 20 - 50 °C / |Inert atmosphere 4.1: Dess-Martin periodane / dichloromethane / 2 h / 0 - 20 °C / |Inert atmosphere 5.1: L-Selectridereg; / tetrahydrofuran / 4 h / -78 °C / |Inert atmosphere 6.1: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 °C 7.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / -78 - 20 °C / |Inert atmosphere View Scheme

1.1: triphenylphosphine / tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere 1.2: 0.42 h / 20 °C / |Inert atmosphere; |Sonication 2.1: triphenylphosphine; gold(III) chloride; silver trifluoromethanesulfonate / dichloromethane / 7 h / 20 - 50 °C / |Inert atmosphere 3.1: Dess-Martin periodane / dichloromethane / 2 h / 0 - 20 °C / |Inert atmosphere 4.1: L-Selectridereg; / tetrahydrofuran / 4 h / -78 °C / |Inert atmosphere 5.1: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 °C 6.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / -78 - 20 °C / |Inert atmosphere View Scheme

1: Dess-Martin periodane / dichloromethane / 2 h / 0 - 20 °C / |Inert atmosphere 2: L-Selectridereg; / tetrahydrofuran / 4 h / -78 °C / |Inert atmosphere 3: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 °C 4: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / -78 - 20 °C / |Inert atmosphere View Scheme

1: L-Selectridereg; / tetrahydrofuran / 4 h / -78 °C / |Inert atmosphere 2: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 °C 3: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / -78 - 20 °C / |Inert atmosphere View Scheme

1: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / -78 - 20 °C / |Inert atmosphere View Scheme

acetic acid in ethanol T=20°C; 48 h;