(S)-1-苯基-1,3-丙二醇合成路线 （共 41 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Kamal, Ahmed; Khanna; Ramu
Tetrahedron Asymmetry, 2002 , vol. 13, # 18 p. 2039 - 2051
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C;
参考文献
Sann, Christine Le; Munoz, Dulce M.; Saunders, Natalie; Simpson, Thomas J.; Smith, David I.; Soulas, Florilene; Watts, Paul; Willis, Christine L.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 9 p. 1719 - 1728
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 1 h;
参考文献
Xu, Chengfu; Yuan, Chengye
Tetrahedron, 2005 , vol. 61, # 8 p. 2169 - 2186
反应条件
in methanol; di-isopropyl ether; water
参考文献
Takasago International Corporation
Patent: US5324870 A1, 1994 ;
反应条件
in methanol; di-isopropyl ether; water
参考文献
Takasago International Corporation
Patent: US5286888 A1, 1994 ;
反应条件
1: <Rh((S,S)-chiraphos)>2(ClO4)2 / acetone / 0.3 h / 25 °C 2: KF, KHCO3, 30percent aq. H2O2 / methanol; tetrahydrofuran / 18 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 114, # 6 p. 2121 - 2128
反应条件
1: triethylamine / diethyl ether / 18 h / Ambient temperature 2: <Rh((S,S)-chiraphos)>2(ClO4)2 / acetone / 0.3 h / 25 °C 3: KF, KHCO3, 30percent aq. H2O2 / methanol; tetrahydrofuran / 18 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 114, # 6 p. 2121 - 2128
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in ethylene glycol dimethyl ether 0 deg C, 0.5 h, RT, 4.5 h;
参考文献
Matsuura, Fumiyoshi; Hamada, Yasumasa; Shioiri, Takayuki
Tetrahedron, 1993 , vol. 49, # 36 p. 8211 - 8222
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 17 h; Ambient temperature;
参考文献
Chan, T. H.; Nwe, K. T.
Journal of Organic Chemistry, 1992 , vol. 57, # 23 p. 6107 - 6111
反应条件
1.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: tetrahydrofuran; hexane / 1 h / -78 °C 2.1: DCC; 4-(dimethylamino)pyridine / CH2Cl2 / 20 °C 3.1: Candida rugosa lipase; MgCl2 / H2O; diisopropyl ether / 24 h / 30 °C 4.1: 95 percent / LiAlH4 / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 61, # 8 p. 2169 - 2186
