1: 95 percent / HCl / acetone / 6 h / Ambient temperature 2: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 10 min, 2.) THF, 0 deg C, 30 min 3: 50 percent / LDA / tetrahydrofuran / 0.17 h / -78 °C 4: pyridine / 1 h / 0 °C 5: 1.) LiBr, Li2CO3, DMF, 2.) H2 / 2.) 5percent Pd/C / 1.) 150 deg C, 4 h, 2.) ethyl acetate, RT, 8 h 7: 5percent sodium amalgam / tetrahydrofuran; methanol / 9 h / -20 - 20 °C 8: n-Bu4NF / tetrahydrofuran / 2 h / Ambient temperature View Scheme