1: 61 percent / CH3ONa / 13 h / 130 °C 2: H2, 0.1 N NaOH / 10percent Pd/C / aq. ethanol / 2 h / 23 °C / 2052 Torr View Scheme

sodium hydroxide; hydrogen; palladium on activated charcoal in ethanol T=23°C; P=2052 Torr; 2 h;

sodium methylate T=130°C; 13 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: 70 percent / POBr₃ <br />2: 73 percent / CH₃ONa / methanol / 1.25 h / 140 &deg;C / under pressure in the sealed vessel<br /> <br /> &nbsp;