5,6-环氧-5,6-二氢苯并[a]蒽合成路线 （共 13 条）
反应条件
lithium in tetrahydrofuran 1.) 0 deg C, 3 h, 2.) -18 deg C, 6 d;
参考文献
Elmalak, Omar; Rabinovitz, Mordecai; Blum, Jochanan
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 1 p. 291 - 292
反应条件
water; Alkarsodyl; calf thymus DNA
T=23°C; pH 7.1; effect of native DNA, denaturated DNA, and reaction time; Rate constantProduct distribution;
参考文献
Urano, Shigeyuki; Price, Harry L.; Fetzer, Sharon M.; Briedis, Anita V.; Milliman, Ann; LeBreton, Pierre R.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3881 - 3893
反应条件
water in 1,4-dioxane
T=25°C; solvent effects (acid-catalyzed methanolysis), substituent effects; Rate constantProduct distribution;
参考文献
Nashed, Nashaat T.; Balani, Suresh K.; Loncharich, Richard J.; Sayer, Jane M.; Shipley, David Y.; Mohan, Ram S.; Whalen, Dale L.; Jerina, Donald M.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3910 - 3919
反应条件
water in 1,4-dioxane
T=25°C; solvent effects (acid-catalyzed methanolysis), substituent effects; Rate constantProduct distribution;
参考文献
Nashed, Nashaat T.; Balani, Suresh K.; Loncharich, Richard J.; Sayer, Jane M.; Shipley, David Y.; Mohan, Ram S.; Whalen, Dale L.; Jerina, Donald M.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3910 - 3919
反应条件
water; Alkarsodyl; calf thymus DNA
T=23°C; pH 7.1; effect of native DNA, denaturated DNA, and reaction time; Rate constantProduct distribution;
参考文献
Urano, Shigeyuki; Price, Harry L.; Fetzer, Sharon M.; Briedis, Anita V.; Milliman, Ann; LeBreton, Pierre R.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3881 - 3893
反应条件
1: CH3ONa / 1) 50 deg C, 1 h, 2) room temperature, overnight
2: aq. HCl / acetone / 2 h / 50 °C
View Scheme
参考文献
Weems, Henri B.; Mushtaq, Mohammad; Yang, Shen K.
Analytical Chemistry, 1987 , vol. 59, # 22 p. 2679 - 2688
反应条件
ethanesulfonic acid in acetonitrile
T=25°C; other arene oxides; Rate constantMechanism;
参考文献
Nashed, Nashaat T.; Sayer, Jane M.; Jerina, Donald M.
Journal of the American Chemical Society, 1993 , vol. 115, # 5 p. 1723 - 1730
反应条件
water in 1,4-dioxane
T=25°C; solvent effects (acid-catalyzed methanolysis), substituent effects; Rate constantProduct distribution;
参考文献
Nashed, Nashaat T.; Balani, Suresh K.; Loncharich, Richard J.; Sayer, Jane M.; Shipley, David Y.; Mohan, Ram S.; Whalen, Dale L.; Jerina, Donald M.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3910 - 3919
反应条件
methanesulfonic acid in acetonitrile
T=25°C; solvent effects (acid-catalyzed methanolysis), substituent effects; Rate constantProduct distribution;
参考文献
Nashed, Nashaat T.; Balani, Suresh K.; Loncharich, Richard J.; Sayer, Jane M.; Shipley, David Y.; Mohan, Ram S.; Whalen, Dale L.; Jerina, Donald M.
Journal of the American Chemical Society, 1991 , vol. 113, # 10 p. 3910 - 3919
反应条件
ethylenediaminetetraacetic acid; tris(hydroxymethyl)methylamine hydrochloride in sodium hydroxide
T=23°C; Rearrangement; pH=7.3; Kinetics;
参考文献
Fernando, Harshica; Huang, Chao-Ran; Milliman, Ann; Shu, Luchuan; LeBreton, Pierre R.
Chemical Research in Toxicology, 1996 , vol. 9, # 8 p. 1391 - 1402
