(2R,3S)-rel-3-(4-甲氧基苯基)-2-环氧乙烷羧酸甲酯合成路线 （共 26 条）
反应条件
Bacillus megaterium ECU1001 cell-free extract in potassium phosphate buffer; dimethyl sulfoxide T=30°C; pH=7; 0.0833333 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Zhao, Jing; Chu, Yan-Yan; Li, Ai-Tao; Ju, Xin; Kong, Xu-Dong; Pan, Jiang; Tang, Yun; Xu, Jian-He
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1510 - 1518
反应条件
in cyclohexane; water 1.5 h; Ambient temperatureenzymatic hydrolysis by lipase from Candida cylindracea (CCL), pH 7.4, other enzymes; enzymatic transesterification;
参考文献
Gentile; Giordano; Fuganti; Ghirotto; Servi
Journal of Organic Chemistry, 1992 , vol. 57, # 24 p. 6635 - 6635
反应条件
1: aq. FeCl3 / chlorobenzene / 0.75 h / 115 °C 2: methanesulfonic acid / chlorobenzene / 8 h / Heating 3: 93.9 percent / aq. K2CO3 / ethyl acetate / 8 h / Heating View Scheme
参考文献
Yamada, Shin-Ichi; Yoshioka, Ryuzo; Shibatani, Takeji
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 12 p. 1922 - 1927
反应条件
in toluene 0.166667 h; Irradiationmicrowave, 350 watts; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 37, # 35 p. 6413 - 6416
反应条件
sodium methylate in methanol 17 h; Ambient temperature;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 4 p. 1085 - 1089
反应条件
sodium methylate in methanol 17 h; Ambient temperature;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 4 p. 1085 - 1089
