N-[2-(4-甲氧基-1H-吲哚-3-基)乙基]-N-甲基-2-丙胺合成路线 (共 5 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=2585.7 Torr; 15 h; Yield given;
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
1: 95 percent / tert-butylcatechol / xylene / 3 h / Heating
2: H2 / 10 percent Pd/C / ethanol / 12 h / 2585.7 Torr
3: K2CO3 / H2O; toluene / 15 h / Ambient temperature
4: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating
5: H2 / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr
View Scheme
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
1: K2CO3 / H2O; toluene / 15 h / Ambient temperature
2: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating
3: H2 / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr
View Scheme
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
1: H2 / 10 percent Pd/C / ethanol / 12 h / 2585.7 Torr
2: K2CO3 / H2O; toluene / 15 h / Ambient temperature
3: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating
4: H2 / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr
View Scheme
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896
反应条件
1: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating
2: H2 / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr
View Scheme
参考文献
Repke, David B.; Grotjahn, Douglas B.; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 892 - 896