3-(叔丁基二甲基硅氧基)苯甲醛合成路线 （共 18 条）
反应条件
sodium hydride in tetrahydrofuran T=20°C;
参考文献
Kishore Kumar; Natarajan, Amarnath
Tetrahedron Letters, 2008 , vol. 49, # 13 p. 2103 - 2105
反应条件
in tetrahydrofuran T=20°C; Wittig olefination; 6 h;
参考文献
Pandey, Rajesh Kumar; Upadhyay, Puspesh Kumar; Kumar, Pradeep
Tetrahedron Letters, 2003 , vol. 44, # 33 p. 6245 - 6246
反应条件
Oxonereg;; In(OTf)3 2 h; Reflux;
参考文献
Mineno, Tomoko; Sakai, Mai; Ubukata, Akira; Nakahara, Kazuhide; Yoshimitsu, Hitoshi; Kansui, Hisao
Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 8 p. 870 - 872
反应条件
1.1: 84 percent / methanol / 0.17 h / 20 °C 2.1: LiHMDS / tetrahydrofuran / -78 - 20 °C 2.2: 45 percent / BnEt3NCl / toluene / 60 h / 40 °C 3.1: aq. HCl / dioxane / 16 h / 20 °C 4.1: 70 mg / aq. HCl / dioxane / 160 h / Heating View Scheme
参考文献
Adams, Luke A.; Aggarwal, Varinder K.; Bonnert, Roger V.; Bressel, Bettina; Cox, Russell J.; Shepherd, Jon; De Vicente, Javier; Walter, Magnus; Whittingham, William G.; Winn, Caroline L.
Journal of Organic Chemistry, 2003 , vol. 68, # 24 p. 9433 - 9440
反应条件
1.1: 84 percent / methanol / 0.17 h / 20 °C 2.1: LiHMDS / tetrahydrofuran / -78 - 20 °C 2.2: 45 percent / BnEt3NCl / toluene / 60 h / 40 °C 3.1: aq. HCl / dioxane / 16 h / 20 °C 4.1: 70 mg / aq. HCl / dioxane / 160 h / Heating View Scheme
参考文献
Adams, Luke A.; Aggarwal, Varinder K.; Bonnert, Roger V.; Bressel, Bettina; Cox, Russell J.; Shepherd, Jon; De Vicente, Javier; Walter, Magnus; Whittingham, William G.; Winn, Caroline L.
Journal of Organic Chemistry, 2003 , vol. 68, # 24 p. 9433 - 9440
反应条件
1.1: 90 percent / tetrahydrofuran / 6 h / 20 °C 2.1: 97 percent / (DHQD)2PHAL; K3Fe(CH)6; K2CO3 / OsO4 / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C 3.1: 98 percent / dibutyltin oxide; NEt3 / CH2Cl2 / 0.75 h / 20 °C 4.1: 90 percent / AcOH / H2O; tetrahydrofuran / 10 h / 60 °C 5.1: 98 percent / NaI / acetone / 6 h / Heating 6.1: H2O; tetrahydrofuran / 3 h / 20 °C 6.2: 90 percent / methanolic HCl / 20 °C View Scheme
参考文献
Pandey, Rajesh Kumar; Upadhyay, Puspesh Kumar; Kumar, Pradeep
Tetrahedron Letters, 2003 , vol. 44, # 33 p. 6245 - 6246
反应条件
anhydrous lithium acetate in water; N,N-dimethyl-formamide T=25°C; 8 h; Inert atmosphere;
参考文献
Wang, Bing; Sun, Hui-Xia; Sun, Zhi-Hua
Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1781 - 1784
反应条件
1: 91 percent / Mg / diethyl ether / 20 °C 2: 86 percent / PCC / CH2Cl2 / 20 °C View Scheme
参考文献
Siles, Rogelio; Chen, Shen-En; Zhou, Ming; Pinney, Kevin G.; Trawick, Mary Lynn
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 16 p. 4405 - 4409
反应条件
1: With triphenylphosphine in dichloromethane T=0 - 20°C; Ramirez-Corey-Fuchs reaction; 0.5 h; 2: With lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=-78°C; Ramirez-Corey-Fuchs reaction; 2 h; 3: With ammonium chloride in tetrahydrofuran; n-heptane; ethylbenzene Ramirez-Corey-Fuchs reaction;
参考文献
Xia, Yan; Jin, Yinglan; Kaur, Navneet; Choi, Yongseok; Lee, Kyeong
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2386 - 2396
反应条件
1: triphenylphosphine / dichloromethane / 0.5 h / 0 - 20 °C 2: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 2 h / -78 °C View Scheme
参考文献
Xia, Yan; Jin, Yinglan; Kaur, Navneet; Choi, Yongseok; Lee, Kyeong
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2386 - 2396
