3,3-diphenyloxolan-2-one合成路线 （共 18 条）
反应条件
ethanol; water T=160°C; unter Druck;
参考文献
Dupre et al.
Journal of the Chemical Society, 1949 , p. 500,505
反应条件
aluminum tri-bromide 50 h; Ambient temperature;
参考文献
Node, Manabu; Nishide, Kiyoharu; Ochiai, Masahito; Fuji, Kaoru; Fujita, Eiichi
Journal of Organic Chemistry, 1981 , vol. 46, p. 5163 - 5166
反应条件
1: hydrogen bromide; acetic acid / 48 h / 20 °C 2: thionyl chloride / chloroform / 4 h / |Reflux 3: sodium carbonate / water; toluene / 0 - 20 °C 4: sodium hydroxide / water / pH 12 5: hydrogenchloride / chloroform / 1 h / |Reflux 6: potassium iodide; isobutyl methylketone; sodium carbonate / 80 °C / |Dean-Stark; |Reflux 7: ammonia / water View Scheme
参考文献
Wang, Min; Gao, Mingzhang; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5259 - 5263
反应条件
1: hydrogen bromide; acetic acid / 48 h / 20 °C 2: thionyl chloride / chloroform / 4 h / |Reflux 3: sodium carbonate / water; toluene / 0 - 20 °C 4: isobutyl methylketone; sodium carbonate / 80 °C / |Dean-Stark; |Reflux View Scheme
参考文献
Wang, Min; Gao, Mingzhang; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5259 - 5263
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5607939 A1, 1997 ;
反应条件
aluminum oxide; sodium hydroxide; polymethylhydrosiloxane; (.eta.(5)-C5H5)2Ti(OC6H4Cl-p)2; tetrabutyl ammonium fluoride
Mechanism;
参考文献
Verdaguer, Xavier; Berk, Scott C.; Buchwald, Stephen L.
Journal of the American Chemical Society, 1995 , vol. 117, # 50 p. 12641 - 12642
反应条件
ammonia; zinc(II) chloride
T=225°C; unter Druck;
参考文献
ABBOTT LABORATORIES
Patent: US2011/230459 A1, 2011 ;
Location in patent: Page/Page column 23 ;
反应条件
ethanol; water
T=180°C; unter Druck;
参考文献
Dupre et al.
Journal of the Chemical Society, 1949 , p. 500,505
