iodine; triethylamine in methanol T=20°C; 0.333333 h;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: 99 percent / NEt₃; DMAP / CH₂Cl₂ / 3 h / 20 &deg;C<br />2.1: 86 percent / ammonia (g) / CH₂Cl₂ / 18 h / -78 - 20 &deg;C<br />3.1: 95 percent / NEt₃ / CH₂Cl₂ / 4 h / -78 - 20 &deg;C<br />4.1: nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 &deg;C<br />4.2: 89 percent / tetrahydrofuran; hexane / 16 h / -78 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: 95 percent / NEt₃ / CH₂Cl₂ / 4 h / -78 - 20 &deg;C<br />2.1: nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 &deg;C<br />2.2: 89 percent / tetrahydrofuran; hexane / 16 h / -78 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1.1: Mg / diethyl ether<br />1.2: 69 percent / diethyl ether / 16 h / -78 - 20 &deg;C<br />2.1: 82 percent / hydroxylamine hydrochloride / ethanol; pyridine / 2 h / 60 &deg;C<br />3.1: 99 percent / NEt₃; DMAP / CH₂Cl₂ / 3 h / 20 &deg;C<br />4.1: 86 percent / ammonia (g) / CH₂Cl₂ / 18 h / -78 - 20 &deg;C<br />5.1: 95 percent / NEt₃ / CH₂Cl₂ / 4 h / -78 - 20 &deg;C<br />6.1: nBuLi / tetrahydrofuran; hexane / 0.5 h / -78 &deg;C<br />6.2: 89 percent / tetrahydrofuran; hexane / 16 h / -78 &deg;C<br /> <br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '11192214', constants.ctx, '0')">3-(4-bromophenyl)-3-(trifluoromethyl)-1,2-bis(trimethylsilyl)diaziridine</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-78&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1900390', constants.ctx, '0')">carbon dioxide</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-78&deg;C;&nbsp;16&nbsp;h;&nbsp;&nbsp;Further stages.;&nbsp;<br /> &nbsp;