(3R,4R)-4-苯甲酰氧基-3-(1-叔丁基二甲基硅氧基]乙基)环丁胺-2-酮合成路线 （共 9 条）
反应条件
MPPA in ethyl acetate 18 h;
参考文献
Hanessian, Stephen; Bedeschi, Angelo; Battistini, Carlo; Mongelli, Nicola
Journal of the American Chemical Society, 1985 , vol. 107, # 5 p. 1438 - 1439
反应条件
oxygen; benzaldehyde; iron(III) oxide in benzene P=760 Torr; Ambient temperature;
参考文献
Murahashi, Shun-Ichi; Oda, Yoshiaki; Naota, Takeshi
Tetrahedron Letters, 1992 , vol. 33, # 49 p. 7557 - 7560
反应条件
dicyclohexyl-carbodiimide in dichloromethane T=0°C; 0.25 h;
参考文献
Shiozaki
Synthesis, 1990 , # 8 p. 691 - 693
反应条件
SPB; acetic acid T=70°C; Baeyer-Villiger Oxidation; 1 h; Product distribution / selectivity;
参考文献
WO2008/7836 A1, ;
Page/Page column 9-10 ;
反应条件
1: 87 percent / ceric ammonium nitrate / acetonitrile / -10 °C 2: 89 percent / monoperphthalic acid / ethyl acetate / 18 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 107, # 5 p. 1438 - 1439
反应条件
zinc(II) iodide in acetonitrile 48 h; Ambient temperature;
参考文献
Kita, Yasuyuki; Shibata, Norio; Yoshida, Naoki; Tohjo, Takashi
Tetrahedron Letters, 1991 , vol. 32, # 21 p. 2375 - 2378
Title/Abstract Full Text View citing articles Show Details
Kita; Shibata; Yoshida; Tohjo
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1733 - 1736
反应条件
1: 95 percent / 0.2M aq. NaOH / ethanol / 15 h / 60 °C 2: 54 percent / 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 0.25 h / 0 °C View Scheme
参考文献
Synthesis, , # 8 p. 691 - 693
反应条件
1: 48 percent / diethyl ether; cyclohexane / 0.17 h / 0 °C 2: 88 percent / 3-chloroperoxybenzoic acid / CHCl3 / 3 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 8 p. 691 - 693
反应条件
sodium acetate in acetic acid T=70°C; 2 h; Product distribution / selectivity;
参考文献
CHOONGWAE PHARMA CORPORATION
Patent: WO2008/7836 A1, 2008 ;
Location in patent: Page/Page column 10 ;
