7-三甲基硅基炔基-1H-吲唑合成路线 （共 5 条）
反应条件
copper(l) iodide; triethylamine; triphenylphosphine in acetonitrile
T=20°C; 6 h;
参考文献
Cottyn, Betty; Acher, Francine; Ramassamy, Booma; Alvey, Luke; Lepoivre, Michel; Frapart, Yves; Stuehr, Dennis; Mansuy, Daniel; Boucher, Jean-Luc; Vichard, Dominique
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 11 p. 5962 - 5973
反应条件
1: 98 percent / aq. NaNO2; glacial acetic acid / 0.33 h
2: 75 percent / NH4(+)HCOO(-); H2 / Pd/C / ethanol
3: 71 percent / HCl; H2SO4; NaNO2 / KI / 0 °C
4: 70 percent / Et3N; PPh3; CuI / acetonitrile / 6 h / 20 °C
View Scheme
参考文献
Cottyn, Betty; Vichard, Dominique; Terrier, Francois; Nioche, Pierre; Raman
Synlett, 2007 , # 8 p. 1203 - 1206
反应条件
1: 71 percent / HCl; H2SO4; NaNO2 / KI / 0 °C
2: 70 percent / Et3N; PPh3; CuI / acetonitrile / 6 h / 20 °C
View Scheme
参考文献
Cottyn, Betty; Vichard, Dominique; Terrier, Francois; Nioche, Pierre; Raman
Synlett, 2007 , # 8 p. 1203 - 1206
反应条件
1: 75 percent / NH4(+)HCOO(-); H2 / Pd/C / ethanol
2: 71 percent / HCl; H2SO4; NaNO2 / KI / 0 °C
3: 70 percent / Et3N; PPh3; CuI / acetonitrile / 6 h / 20 °C
View Scheme
参考文献
Cottyn, Betty; Vichard, Dominique; Terrier, Francois; Nioche, Pierre; Raman
Synlett, 2007 , # 8 p. 1203 - 1206
反应条件
methanol; potassium carbonate
T=20°C; 16 h;
参考文献
Cottyn, Betty; Acher, Francine; Ramassamy, Booma; Alvey, Luke; Lepoivre, Michel; Frapart, Yves; Stuehr, Dennis; Mansuy, Daniel; Boucher, Jean-Luc; Vichard, Dominique
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 11 p. 5962 - 5973
