1: 91 percent 2: 90 percent / H2 / Pd/C / ethanol 3: POCl3 / CH2Cl2 / 24 h / Ambient temperature 4: 96 percent / BCl3 / CH2Cl2 / 3 h / Ambient temperature 5: 82 percent / SO2Cl2 6: 91 percent / pyridine / 18 h / Ambient temperature 7: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 8: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

1: 90 percent / H2 / Pd/C / ethanol 2: POCl3 / CH2Cl2 / 24 h / Ambient temperature 3: 96 percent / BCl3 / CH2Cl2 / 3 h / Ambient temperature 4: 82 percent / SO2Cl2 5: 91 percent / pyridine / 18 h / Ambient temperature 6: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 7: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

sodium hydroxide; water in ethanol 18 h; Heating;

1: 94 percent / H2 / Pd/C / ethyl acetate 2: 96 percent / BCl3 / CH2Cl2 / 3 h / Ambient temperature 3: 82 percent / SO2Cl2 4: 91 percent / pyridine / 18 h / Ambient temperature 5: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 6: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

sulfuryl dichloride in dichloromethane 12 h;

1: POCl3 / CH2Cl2 / 24 h / Ambient temperature 2: 96 percent / BCl3 / CH2Cl2 / 3 h / Ambient temperature 3: 82 percent / SO2Cl2 4: 91 percent / pyridine / 18 h / Ambient temperature 5: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 6: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

1: 96 percent / BCl3 / CH2Cl2 / 3 h / Ambient temperature 2: 82 percent / SO2Cl2 3: 91 percent / pyridine / 18 h / Ambient temperature 4: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 5: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

1: 82 percent / SO2Cl2 2: 91 percent / pyridine / 18 h / Ambient temperature 3: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 4: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

1: 91 percent / pyridine / 18 h / Ambient temperature 2: NaClO2, NH3SO3H / tetrahydrofuran; H2O / 5.5 h / Ambient temperature 3: NaOH/H2O / ethanol / 0.75 h / Ambient temperature View Scheme

1: 98 percent / SO2Cl2 / 3 h / Ambient temperature 2: 37 percent / NaOH/H2O / ethanol / 18 h / Heating View Scheme